It’s been a long year for basically everyone — and especially for Dr. Henry Walke. For months on end, Walke has been pulling 13-hour work days as the COVID-19 incident response manager at the Centers for Disease Control and Prevention, a job he took on last July. He never expected the job to last this long. “The scale of this pandemic is mind-boggling, and it’s affected all of us — every facet of our work and home,” he says. Walke is heading up the largest and most challenging outbreak response in the agency’s history — an all-agency effort involving more than 8,000 employees, working to guide the U.S. out of a public health emergency that has claimed more than 550,000 lives.