Black patients are some of the most reluctant to participate in clinical trials, according to FDA statistics. And their inclusion in the coronavirus vaccine trials has been a stated priority for the pharmaceutical companies involved, since African American communities, along with Latinos, have suffered disproportionately from the pandemic. But the trials are moving at a pace that is unprecedented for medical research, with the Trump administration’s vaccine acceleration effort dubbed “Operation Warp Speed.” Yet recruiting minority participants into these ongoing trials requires sensitivity to a legacy of mistrust based on past and current medical mistreatment, and that trust-building cannot be rushed.